Design the Process.
Use Cases.
From process development and tech transfer to suppliers and academia, BioSolve® Process delivers in silico insight across the entire biopharmaceutical ecosystem. Explore the use cases below.
Select your audience, then choose a topic on the left to see how BioSolve® Process supports your team.
Developing future-proof processes is critical in a rapidly evolving biopharmaceutical industry. With BioSolve® Process (BSP), process development users can set objectives to identify and target innovation where it will maximize the positive impact on both your current and future processes. Therefore, you can make informed decisions when evaluating process technologies to both reduce risk and provide an internal rationale for a particular decision.
Our process development users leverage BSP for the following use cases:
- Informing technology alternative choices
- Evaluating process options prior to commitment on the bench
- Understanding scalability at an early stage to support design for manufacturability
- Informing the influence of buffer and media selection
- Understanding the financial and sustainability impact of stainless steel vs. single-use and fed-batch vs. intensified processing
- Illustrating the impact of automation level on process duration and number of batches.
See how we can help process development scientists.
Many Manufacturing Science & Technology (MSAT) professionals find themselves inheriting a process from an R&D team that did not have access to tools such as BioSolve® Process (BSP). These developers must determine how to truly scale the process and fit it to a different capital infrastructure than initially contemplated. With BSP you can quickly evaluate how the current process translates to larger manufacturing scales, and even build the bill of materials. In addition, you can determine the cost of goods for various manufacturing options, evaluate the facility fit, and determine how to meet company eco-design goals.
Our MSAT users leverage BSP for the following use cases:
- Determining if existing vessels or single use systems in the facility are suitable to manage process scale buffer and media
- Reducing risk when scaling a process from early phase to commercial manufacturing scale
- Conducting advanced scenario analysis to gain business insights that can be present to inform senior management of “what if” scenarios
- Quickly understanding the environmental impact of a proposed process change.
Interested to collaborate with Biopharm Services?
Tech transfer involves migrating both knowledge and processes from development to manufacturing, or from one site to another. This can be a challenging endeavor as process equipment and operator knowledge are rarely identical between different sites. By automatically generating the bill of materials for a given process, BioSolve® Process (BSP) saves time and improves consistency, thereby streamlining tech transfer. With BioSolve® Connect (BSC), modelled unit operations can be shared across sites, transferring knowledge seamlessly through the cloud.
Our tech transfer users leverage BSP for the following use cases:
- Rapidly creating bills of materials so your supply chain colleagues can initiate procurement of raw materials and consumables for the batch
- Evaluating how the transferred process can fit with the existing equipment assets using our updated equipment cost database
- Integrating with BSC to share unit operations and manage all manufacturing information in the enterprise.
Interested to collaborate with Biopharm Services?
For CDMOs it is paramount that informed decisions are made quickly, saving time and resources. The consequences of not doing so are costly and can have a dramatic impact on the business. BioSolve® Process (BSP) can be used to evaluate your existing commercial processes and unearth opportunities to reduce cost, while increasing productivity through implementation of new technologies or process optimization.
In conjunction with our networked data storage application BioSolve® Connect (BSC), the software can allow CDMO users to manage the breadth of information and data that manufacturing processes output:
- Sharing and managing cost datasets, process models, and unit operations across the organization’s global manufacturing network
- Collaborating with fellow manufacturing process modellers throughout your organization
- Managing geographical cost data which can used with BSP to assess the economics of a process at different global sites.
See how we can make CDMO businesses more profitable.
Improving the sustainability of bioprocessing is at the forefront of biopharma stakeholders. With add-on modules such as Eco Concept, you can now evaluate and report on your process’s environmental sustainability footprint.
Energy Load
Determining your facility’s energy load & operating carbon footprint
PMI
Calculating Process Mass Intensity (PMI) of your process
Water Usage
Understanding water usage and calculating CO2e
For suppliers of raw materials, consumables and equipment to biopharmaceutical manufacturers, having a deep understanding of the biomanufacturers’ process is invaluable.
With BioSolve® Process (BSP), you can model your technology across various modalities to understand your product’s impact on processing time, cost, and yield. This allows product managers to understand key cost drivers and demonstrate value of their products, which can be utilized in marketing materials for messaging purposes.
Our marketing and product management users from suppliers leverage BSP for the following use cases:
- Comparing their technologies to those of other suppliers in a typical bioprocess
- Understanding the pain points of a process and deriving value of their product offering
- Understanding the capabilities of their product from the biomanufacturers’ perspective without having to observe on-site
- Gaining insight into how biomanufacturers want to deploy your technology.
Interested to collaborate with Biopharm Services?
Suppliers are a key source of innovation in biopharmaceutical manufacturing – especially when it comes to new modalities such as viral vectors, mRNA, and ADCs. Such innovation leads to the development of new product technologies across raw materials, consumables, and equipment. BioSolve® Process (BSP) can help identify unmet process technology needs for new modalities to inform your product development strategy. Additionally, add-on modules such as Eco Concept can help you calculate your product’s contribution to a process’s eco-friendliness.
Our new product development users leverage BSP for the following use cases:
- Informing marketing and pricing strategy for new raw materials, consumables, or equipment
- Quickly understanding the environmental impact of your product to augment your marketing message
- Conducting advanced scenario analyses to gain business insights that can be presented to inform senior management of “what if” scenarios.
Want to inform your product development strategy?
Many universities today offer education, training, and professional development opportunities for students and professionals who want to stay abreast of the latest trends in the bioprocessing industry. With BioSolve® Process and its various add-on modules such as Optimizer, these academic programs can offer cutting-edge modelling capabilities including sustainability/eco-design, Bayesian optimization, and mechanistic modelling to their learners.
Our academic program management users leverage BSP for the following use cases:
- Deepening the understanding of complex bioprocesses beyond the basics
- Diving into highly technical multi-objective modelling and optimization using Bayesian inference statistical methods
- Determining a facility’s energy load, operating carbon footprint, water usage, and CO2e.
Interested to collaborate with Biopharm Services?
